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1

Protein Aggregation

Merlini, Giampaolo, Bellotti, Vittorio, Andreola, Alessia, Palladini, Giovanni, Obici, Laura, Casarini, Simona, Perfetti, Vittorio

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2001

Language:

english

File:

PDF, 608 KB

english, 2001

2

Enhanced toxicity of silver nanoparticles in transgenic Caenorhabditis elegans expressing amyloidogenic proteins

Soria, Cristina, Coccini, Teresa, De Simone, Uliana, Marchese, Loredana, Zorzoli, Irene, Giorgetti, Sofia, Raimondi, Sara, Mangione, P. Patrizia, Ramat, Stefano, Bellotti, Vittorio, Manzo, Luigi, Stop

Journal:

Year:

2015

Language:

english

File:

PDF, 918 KB

english, 2015

3

The Polyphenol Oleuropein aglycone hinders the growth of toxic Transthyretin amyloid assemblies

Leri, Manuela, Nosi, Daniele, Natalello, Antonino, Porcari, Riccardo, Ramazzotti, Matteo, Chiti, Fabrizio, Bellotti, Vittorio, Doglia, Silvia Maria, Stefani, Massimo, Bucciantini, Monica

Journal:

The Journal of Nutritional Biochemistry

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

4

Antiamyloidogenic and proamyloidogenic chaperone effects of C-reactive protein and serum amyloid P component

Ozawa, Daisaku, Nomura, Ryo, Mangione, P. Patrizia, Hasegawa, Kazuhiro, Okoshi, Tadakazu, Porcari, Riccardo, Bellotti, Vittorio, Naiki, Hironobu

Journal:

Year:

2017

Language:

english

File:

PDF, 552 KB

english, 2017

5

Affinity capillary electrophoresis is a powerful tool to identify transthyretin binding drugs for potential therapeutic use in amyloidosis

Ersilia De Lorenzi, Chiara Galbusera, Vittorio Bellotti, Palma Mangione, Gabriella Massolini, Elena Tabolotti, Alessia Andreola, Gabriele Caccialanza

Journal:

ELECTROPHORESIS

Year:

2000

Language:

english

File:

PDF, 170 KB

english, 2000

6

Capillary electrophoresis investigation of a partially unfolded conformation of β2-microglobulin

Ersilia De Lorenzi, Silvia Grossi, Gabriella Massolini, Sofia Giorgetti, Palma Mangione, Alessia Andreola, Fabrizio Chiti, Vittorio Bellotti, Gabriele Caccialanza

Journal:

ELECTROPHORESIS

Year:

2002

Language:

english

File:

PDF, 614 KB

english, 2002

7

Reversal of nephrotic syndrome due to reactive amyloidosis (AA-type) after excision of localized Castleman's disease

Vittorio Perfetti, Vittorio Bellotti, Anna Maggi, Eloisa Arbustini, Fabrizio De Benedetti, Marco Paulli, Maria Gabriella Marinone, Dr. Giampaolo Merlini

Journal:

American Journal of Hematology

Year:

1994

Language:

english

File:

PDF, 584 KB

english, 1994

8

A novel AβPP mutation exclusively associated with cerebral amyloid angiopathy

Laura Obici, Andrea Demarchi, Giulia de Rosa, Vittorio Bellotti, Sabrina Marciano, Simona Donadei, Eloisa Arbustini, Giovanni Palladini, Marta Diegoli, Egidio Genovese, Giancarlo Ferrari, Sergio Cover

Journal:

Annals of Neurology

Year:

2005

Language:

english

File:

PDF, 892 KB

english, 2005

9

Susceptibility to AA amyloidosis in rheumatic diseases: A critical overview

Laura Obici, Sara Raimondi, Francesca Lavatelli, Vittorio Bellotti, Giampaolo Merlini

Journal:

Arthritis Care & Research

Year:

2009

Language:

english

File:

PDF, 185 KB

english, 2009

10

Enhanced molecular chaperone activity of the small heat-shock protein αB-crystallin following covalent immobilization onto a solid-phase support

Megan Garvey, Stefani S. Griesser, Hans J. Griesser, Benjamin Thierry, Matthew R. Nussio, Joseph G. Shapter, Heath Ecroyd, Sofia Giorgetti, Vittorio Bellotti, Juliet A. Gerrard, John A. Carver

Journal:

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

11

Capillary electrophoresis studies on the aggregation process of β-amyloid 1-42 and 1-40 peptides

Stefania Sabella, Milena Quaglia, Cristina Lanni, Marco Racchi, Stefano Govoni, Gabriele Caccialanza, Alberto Calligaro, Vittorio Bellotti, Ersilia De Lorenzi

Journal:

ELECTROPHORESIS

Year:

2004

Language:

english

File:

PDF, 173 KB

english, 2004

12

Search of ligands for the amyloidogenic protein β2-microglobulin by capillary electrophoresis and other techniques

Milena Quaglia, Chiara Carazzone, Stefania Sabella, Raffaella Colombo, Sofia Giorgetti, Vittorio Bellotti, Ersilia De Lorenzi

Journal:

ELECTROPHORESIS

Year:

2005

Language:

english

File:

PDF, 259 KB

english, 2005

13

Sulfonated molecules that bind a partially structured species of β2-microglobulin also influence refolding and fibrillogenesis

Chiara Carazzone, Raffaella Colombo, Milena Quaglia, Palma Mangione, Sara Raimondi, Sofia Giorgetti, Gabriele Caccialanza, Vittorio Bellotti, Ersilia De Lorenzi

Journal:

ELECTROPHORESIS

Year:

2008

Language:

english

File:

PDF, 453 KB

english, 2008

14

Solution structure of β2-microglobulin and insights into fibrillogenesis

Gennaro Esposito, Alessandra Corazza, Paolo Viglino, Giuliana Verdone, Fabio Pettirossi, Federico Fogolari, Ads Makek, Sofia Giorgetti, Palma Mangione, Monica Stoppini, Vittorio Bellotti

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2005

Language:

english

File:

PDF, 344 KB

english, 2005

15

Proteomics of β2-microglobulin amyloid fibrils

Monica Stoppini, Palma Mangione, Maria Monti, Sofia Giorgetti, Loredana Marchese, Patrizia Arcidiaco, Laura Verga, Siro Segagni, Piero Pucci, Giampaolo Merlini, Vittorio Bellotti

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2005

Language:

english

File:

PDF, 405 KB

english, 2005

16

Dialysis-related amyloidosis: From molecular mechanism to therapies

Yuji Goto, Vittorio Bellotti, Rino Esposito

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2005

Language:

english

File:

PDF, 67 KB

english, 2005

17

Detection of fragments of β2-microglobulin in amyloid fibrils

Stoppini, Monica, Arcidiaco, Patrizia, Mangione, Palma, Giorgetti, Sofia, Brancaccio, Diego, Bellotti, Vittorio

Journal:

Kidney International

Year:

2000

Language:

english

File:

PDF, 89 KB

english, 2000

18

Dynamic of β2-Microglobulin Fibril Formation and Reabsorption: The Role of Proteolysis

Vittorio Bellotti, Maurizio Gallieni, Sofia Giorgetti, Diego Brancaccio

Journal:

Seminars in Dialysis

Year:

2001

Language:

english

File:

PDF, 905 KB

english, 2001

19

DE-loop mutations affect β2 microglobulin stability, oligomerization, and the low-pH unfolded form

Carlo Santambrogio, Stefano Ricagno, Matteo Colombo, Alberto Barbiroli, Francesco Bonomi, Vittorio Bellotti, Martino Bolognesi, Rita Grandori

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 382 KB

english, 2010

20

Molecular dynamics simulation of β2-microglobulin in denaturing and stabilizing conditions

Federico Fogolari, Alessandra Corazza, Nicola Varini, Matteo Rotter, Devrim Gumral, Luca Codutti, Enrico Rennella, Paolo Viglino, Vittorio Bellotti, Gennaro Esposito

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2011

Language:

english

File:

PDF, 893 KB

english, 2011

21

Immunoassay methods for determination of serum C-reactive protein levels

Giampaolo Merlini, Franco Pavesi, Cesare Bergonzi, Vittorio Bellotti, Irene Zorzoli, Gianfranco Vadacca, Lia Aguzzi, Remigio Moratti

Journal:

International Journal of Clinical & Laboratory Research

Year:

1984

Language:

english

File:

PDF, 205 KB

english, 1984

22

Micro-heterogeneity and aggregation in β2-microglobulin solutions: effects of temperature, pH, and conformational variant addition

Roberto Piazza, Matteo Pierno, Sara Iacopini, Palma Mangione, Gennaro Esposito, Vittorio Bellotti

Journal:

European Biophysics Journal

Year:

2006

Language:

english

File:

PDF, 423 KB

english, 2006

23

Identification and characterization of a new ligand-binding site in FnbB, a fibronectin-binding adhesin from Streptococcus dysgalactiae

Livia Visai, Edda De Rossi, Viviana Valtulina, Fabrizia Casolini, Simonetta Rindi, Paola Guglierame, Giampiero Pietrocola, Vittorio Bellotti, Giovanna Riccardi, Pietro Speziale

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2003

Language:

english

File:

PDF, 425 KB

english, 2003

24

D-strand perturbation and amyloid propensity in beta-2 microglobulin

Stavros Azinas, Matteo Colombo, Alberto Barbiroli, Carlo Santambrogio, Sofia Giorgetti, Sara Raimondi, Francesco Bonomi, Rita Grandori, Vittorio Bellotti, Stefano Ricagno, Martino Bolognesi

Journal:

Year:

2011

Language:

english

File:

PDF, 405 KB

english, 2011

25

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

Booth, David R., Sunde, Margaret, Bellotti, Vittorio, Robinson, Carol V., Hutchinson, Winston L., Fraser, Paul E., Hawkins, Philip N., Dobson, Christopher M., Radford, Sheena E., Blake, Colin C. F.

Journal:

Year:

1997

File:

PDF, 1.53 MB

1997

26

Targeting C-reactive protein for the treatment of cardiovascular disease

Pepys, Mark B., Hirschfield, Gideon M., Tennent, Glenys A., Ruth Gallimore, J., Kahan, Melvyn C., Bellotti, Vittorio, Hawkins, Philip N., Myers, Rebecca M., Smith, Martin D., Polara, Alessandra

Journal:

Year:

2006

Language:

english

File:

PDF, 853 KB

english, 2006

27

The solution structure of human β2-microglobulin reveals the prodromes of its amyloid transition

Giuliana Verdone, Alessandra Corazza, Paolo Viglino, Fabio Pettirossi, Sofia Giorgetti, Palma Mangione, Alessia Andreola, Monica Stoppini, Vittorio Bellotti, Gennaro Esposito

Journal:

Protein Science

Year:

2002

Language:

english

File:

PDF, 314 KB

english, 2002

28

Structural characterization of κ II Inc, a new amyloid immunoglobulin

Giuseppina Ferri, Monica Stoppini, Paolo Iadarola, Vittorio Bellotti, Giampaolo Merlini

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1989

Language:

english

File:

PDF, 488 KB

english, 1989

29

Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases

Vittorio Bellotti, Fabrizio Chiti

Journal:

Current Opinion in Structural Biology

Year:

2008

Language:

english

File:

PDF, 1.83 MB

english, 2008

30

β 2-microglobulin can be refolded into a native state from ex vivo amyloid fibrils

Vittorio Bellotti, Monica Stoppini, Palma Mangione, Margaret Sunde, Carol Robinson, Lia Asti, Diego Brancaccio, Giuseppina Ferri

Journal:

Year:

1998

Language:

english

File:

PDF, 669 KB

english, 1998

31

Use of a monoclonal antibody against human heart ferritin for evaluating acidic ferritin concentration in human serum

Mario Cazzola, Paolo Arosio, Vittorio Bellotti, Gaetano Bergamaschi, Laura Dezza, Carmelo Iacobello, Giuseppina Ruggeri

Journal:

British Journal of Haematology

Year:

1985

Language:

english

File:

PDF, 578 KB

english, 1985

32

Characteristics of a ferritin-binding protein present in human serum

Vittorio Bellotti, Paolo Arosio, Mario Cazzola, Anna Cozzi, Sonia Levi, Federica Meloni, Elisabetta Zappone

Journal:

British Journal of Haematology

Year:

1987

Language:

english

File:

PDF, 494 KB

english, 1987

33

Relevance of class, molecular weight and isoelectric point in predicting human light chain amyloidogenicity

Vittorio Bellotti, Giampaolo Merlini, Eleonora Bucciarelli, Vittorio Perfetti, Silvana Quaglini, Edoardo Ascari

Journal:

British Journal of Haematology

Year:

1990

Language:

english

File:

PDF, 493 KB

english, 1990

34

A recurrent D-strand association interface is observed in β-2 microglobulin oligomers

Matteo Colombo, Matteo de Rosa, Vittorio Bellotti, Stefano Ricagno, Martino Bolognesi

Journal:

Year:

2012

Language:

english

File:

PDF, 789 KB

english, 2012

35

Characterization of the Two Unique Human Anti-Flavin Monoclonal Immunoglobulins

Monica Stoppini, Vittorio Bellotti, Armando Negri, Giampaolo Merlini, Fred Garver, Giuseppina Ferri

Journal:

Year:

1995

Language:

english

File:

PDF, 722 KB

english, 1995

36

Use of Anti-(β2 Microglobulin) mAb to Study Formation of Amyloid Fibrils

Monica Stoppini, Vittorio Bellotti, Palma Mangione, Giampaolo Merlini, Giuseppina Ferri

Journal:

Year:

1997

Language:

english

File:

PDF, 630 KB

english, 1997

37

Review: Immunoglobulin Light Chain Amyloidosis—The Archetype of Structural and Pathogenic Variability

Vittorio Bellotti, Palma Mangione, Giampaolo Merlini

Journal:

Journal of Structural Biology

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

38

Cardiac immunocyte-derived (AL) amyloidosis: An endomyocardial biopsy study in 11 patients

Eloisa Arbustini, Giampaolo Merlini, Antonello Gavazzi, Maurizia Grasso, Marta Diegoli, Roberta Fasani, Vittorio Bellotti, Gabriella Marinone, Patrizia Morbini, Barbara Dal Bello, Carlo Campana, Victo

Journal:

American Heart Journal

Year:

1995

Language:

english

File:

PDF, 14.86 MB

english, 1995

39

Characterization of apo(a) polymorphism by a modified immunoblotting technique in an italian population sample

Diego Geroldi, Vittorio Bellotti, Paola Buscaglia, Graziella Bonetti, Carmine Gazzaruso, Arianna Caprioli, Pietro Fratino

Journal:

Clinica Chimica Acta

Year:

1993

Language:

english

File:

PDF, 1.40 MB

english, 1993

40

Ultrastructural organization of ex vivo amyloid fibrils formed by the apolipoprotein A-I Leu174Ser variant: an atomic force microscopy study

Annalisa Relini, Ranieri Rolandi, Martino Bolognesi, Manuela Aboudan, Giampaolo Merlini, Vittorio Bellotti, Alessandra Gliozzi

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2004

Language:

english

File:

PDF, 498 KB

english, 2004

41

Single-shot NMR measurement of protein unfolding landscapes

Enrico Rennella, Alessandra Corazza, Luca Codutti, Araldo Causero, Vittorio Bellotti, Monica Stoppini, Paolo Viglino, Federico Fogolari, Gennaro Esposito

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

42

DE loop mutations affect β2-microglobulin stability and amyloid aggregation

Stefano Ricagno, Matteo Colombo, Matteo de Rosa, Enrico Sangiovanni, Sofia Giorgetti, Sara Raimondi, Vittorio Bellotti, Martino Bolognesi

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 339 KB

english, 2008

43

Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation

Stefano Ricagno, Sara Raimondi, Sofia Giorgetti, Vittorio Bellotti, Martino Bolognesi

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 482 KB

english, 2009

44

Lysozyme: A paradigmatic molecule for the investigation of protein structure, function and misfolding

Giampaolo Merlini, Vittorio Bellotti

Journal:

Clinica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 123 KB

english, 2005

45

Folding and Fibrillogenesis: Clues from β2-Microglobulin

Enrico Rennella, Alessandra Corazza, Sofia Giorgetti, Federico Fogolari, Paolo Viglino, Riccardo Porcari, Laura Verga, Monica Stoppini, Vittorio Bellotti, Gennaro Esposito

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

46

The New Apolipoprotein A-I Variant Leu174 → Ser Causes Hereditary Cardiac Amyloidosis, and the Amyloid Fibrils Are Constituted by the 93-Residue N-Terminal Polypeptide

Laura Obici, Vittorio Bellotti, Palma Mangione, Monica Stoppini, Eloisa Arbustini, Laura Verga, Irene Zorzoli, Ernesto Anesi, Giuseppe Zanotti, Carlo Campana, Mario Viganò, Giampaolo Merlini

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 1.62 MB

english, 1999

47

4′-Iodo-4′-Deoxydoxorubicin Disrupts the Fibrillar Structure of Transthyretin Amyloid

Joana Almeida Palha, Dario Ballinari, Nadia Amboldi, Isabel Cardoso, Rui Fernandes, Vittorio Bellotti, Giampaolo Merlini, Maria João Saraiva

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 1.25 MB

english, 2000

48

Structural and functional characterization of three human immunoglobulin κ light chains with different pathological implications

Vittorio Bellotti, Monica Stoppini, Palma P. Mangione, Alessandro Fornasieri, Li Min, Giampaolo Merlini, Giuseppina Ferri

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1996

Language:

english

File:

PDF, 719 KB

english, 1996

49

Molecular Mechanisms of Amyloidosis

Merlini, Giampaolo, Bellotti, Vittorio

Journal:

Boston Medical and Surgical Journal

Year:

2003

Language:

english

File:

PDF, 698 KB

english, 2003

50

Detection of two partially structured species in the folding process of the amyloidogenic protein β2-microglobulin

Fabrizio Chiti, Palma Mangione, Alessia Andreola, Sofia Giorgetti, Massimo Stefani, Christopher M. Dobson, Vittorio Bellotti, Niccolò Taddei

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 294 KB

english, 2001

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